In the movie version, George isn't an ordinary gorilla, but an albino gorilla (I guess to avoid comparisons with King Kong), Lizzie isn't a lizard, but a crocodile (also I guess to avoid comparisons with Godzilla), but Ralph remains a wolf, and Larry (although in a very small role) is a rat like in the original. Everyone except George also has "secondary mutations", but I don't want to spoil the move in case you'd like to watch it.
As for the illustration, here I go again with my "silly animal style". They're based on the movie versions rather than the original video game and I drew them as harmless babies, playing with LEGO bricks, building a city and later destroying it, of course. 😝